First, Ivan Pavlov would sever a dog's esophagus and sew the loose ends to its throat, leaving a pair of adjacent holes that connected, by separate passages, to its mouth and stomach. Then he'd slice through the dog's abdomen, carve a hole in the wall of its stomach, and stitch open another permanent wound.
The dog, left hungry from the night before, would be harnessed to a wooden stand and presented with a bowl of raw meat. No matter how much it ate, it never got full—the dog chewed and swallowed, but the masticated meat would erupt from its esophageal opening and dribble back into the bowl, whereupon the dog would lap it up all over again. In the meantime, a glass tube attached to the animal's stomach opening allowed its gastric secretions to drip into a collecting bottle, so they could be filtered, analyzed, and sold to the public as a remedy for dyspepsia.
As historian Daniel P. Todes writes in Pavlov's Physiology Factory, these thrice-perforated animals enabled a new approach to science—the chronic experiment—and a series of discoveries about the nervous control of digestion for which Pavlov won the Nobel Prize in 1904. (At the time of the award, he hadn't yet shown that animals would drool at the sound of a bell.) In 1935, just before his death, Pavlov approved the design for a monument to his canine test subjects, erected on the grounds of the Institute of Experimental Medicine in St. Petersburg, Russia. A bronze plaque on one side depicts the dogs on laboratory tables, tied to their wooden frames with their fistulas open. "We must painfully acknowledge that, precisely because of its great intellectual development, the best of man's domesticated animals—the dog—most often becomes the victim of physiological experiments," he had written in 1893. "The dog is irreplaceable; moreover it is extremely touching. It is almost a participant in the experiments conducted upon it, greatly facilitating the success of the research by its understanding and compliance."
o one can say exactly how old Pepper was in the summer of 1965, but every member of the Lakavage family remembers her gentle disposition. There were plenty of other dogs racing around their farm at the bottom of Blue Mountain, but the Dalmatian named Pepper—trim and affectionate, pelted with splotches of black—was always Mom's favorite.
Julia Lakavage preferred to take in strays, but she made an exception when she saw Pepper at the decrepit Spatterdash kennel a few miles down the road. Julia and her husband, Peter, lived on 82 acres in the hills above Slatington, Pa., two hours due west of New York City. Peter had a job with Bethlehem Steel; Julia had polished shells there during the World War II, but by the 1960s she was working the night shift as a nurse for the Good Shepherd Home in Allentown. They had four daughters—Star, Carol, Kathy, and Peggy—and a 7-year-old grandson named Michael.
Pepper loved a car ride, and some nights Julia would take her along to the hospital in Allentown. If Julia were the only nurse assigned to the floor, she'd bring the dog on her rounds of nursing home residents and handicapped orphans. The patients loved it, remembers Star. They would call for Pepper as soon as they heard her paws click-clacking along the linoleum hallway. One day, Julia promised, she'd buy "Nurse Pepper" a little white hat.
But Pepper didn't come to work with Julia on the night of Tuesday, June 22, 1965. Sometime that evening, the Lakavage children let Pepper out onto the back porch for her usual evening stroll. When they opened the door half an hour later, the dog wasn't there. "Pepper always came, no matter what," says Michael. "You'd go to let her back in, and she'd be laying on the porch, waiting." For the first time that any of them could remember, Pepper was nowhere to be seen. Michael remembers standing in front of the house, calling into the darkness.
By the next morning, the Lakavages knew for sure that Pepper was gone.
Over the next few days, Julia mobilized her family in a desperate search for the missing dog. According to a short version of the incident that was published five months later, improbably, in the pages of Sports Illustrated, "all during the following week, a heartbroken Mrs. Lakavage advertised and hunted for her dog." Indeed, no one in the family had ever seen Julia so upset. ("Dogs are like family members," she would later tell a newspaper reporter, "children that don't grow up.") The Lakavages fanned out through the woods and along the dirt road that ran past the farm. They checked with the neighbors up the hill and drove to the top of Blue Mountain to call for Pepper from the ridge under the power lines. Julia posted signs and telephoned everyone she knew.
Michael assumed that a neighbor had run over Pepper with a car—there was kid up the road who messed around with muscle cars—but Julia talked to someone who had seen a man loading a Dalmatian into the back of a truck near their farm.
For years, animal welfare groups had been warning of nighttime forays by pet snatchers in unmarked vans. Stolen dogs, they said, were being sold to laboratories and subjected to painful experiments. In 1961, Walt Disney had released 101 Dalmatians—a hugely successful film about pet theft—and the Humane Society of the United States had begun to look into a network of illegal animal dealers operating across Pennsylvania and Maryland. Navy veteran Frank McMahon led the investigation and hired Dec Hogan, a rough-and-tumble nightclub owner, to pose as a dealer in the field. Along with another investigator, Dale Hylton, they began to stake out the rural auctions where stray animals were traded before being shipped off to research laboratories in big cities. The team devoted much of its energy to a notorious Amish market down in Lancaster County, known as the Green Dragon.
Named after a Chinese restaurant on the Atlantic City, N.J., boardwalk, the Dragon had been operating in the town of Ephrata since 1932. (It's still open.) Fridays were auction days, with sales of livestock running all afternoon. The small-animal sale started by 7 p.m.: An auctioneer would set up in the middle of a rectangular pen, about 20 feet by 40 feet, surrounded by bleachers. Crated dogs and cats were rolled inside one by one and put up for bidding.
Hogan remembers thousands of people at the market, Amish vendors selling pies and cookies, and the animal dealers—"grass-roots kinds of guys, doing it for a six-pack of beer"—carting in stray dogs for sale. The winter before Pepper disappeared, investigators had watched one dealer purchase hundreds of dogs at the Green Dragon and pack them into his truck in chicken crates. When he returned home the next morning, the police were waiting; he was arrested for cruel treatment of 7,000 animals on his farm and paid a $67 fine.